Hot and spicy pain signals get blocked in naked mole-rats

Like Marvel’s surly superhero Luke Cage, naked mole-rats are seemingly indestructible, hairless creatures that are impervious to certain kinds of pain. This last power has puzzled researchers, because like other mammals, mole-rats have functional versions of a protein called TRPV1, which responds to painfully hot stimuli. It turns out that a different protein, TrkA, is […]

In a first, mouse eggs grown from skin cells

For the first time, researchers have grown eggs entirely in a lab dish. Skin-producing cells called fibroblasts from the tip of an adult mouse’s tail have been reprogrammed to make eggs, Japanese researchers report online October 17 in Nature. Those eggs were fertilized and grew into six healthy mice. The accomplishment could make it possible […]

Scientists need to redraw picture of cell’s biggest organelle

Textbook drawings of the cell’s largest organelle might need to be updated based on new images. Super-resolution shots of the endoplasmic reticulum reveal tightly packed tubes where previous pictures showed plain flat sheets, scientists report in the Oct. 28 Science. The finding helps explain how the endoplasmic reticulum, or ER, reshapes itself in response to […]

First known fossilized dinosaur brain unearthed, scientists claim

SALT LAKE CITY — Dinosaur smarts may be a mystery, but their brains, at least, are now more concrete. A chunk of petrified brain tissue discovered in a tidal pool in southern England is the first reported from a dinosaur, researchers claim. The roughly 133-million-year-old fossil preserves the brain’s wrinkled topology, said paleontologist David Norman, […]

Whirlpools might have stirred up baby universe’s soup

Complex swirls and vortices can appear in the souplike phase of matter that existed just moments after the Big Bang. Computer simulations show that this substance, called the quark-gluon plasma, can contain “the hottest smoke ring in nature,” says Xin-Nian Wang of Lawrence Berkeley National Laboratory, coauthor of a paper published in the Nov. 4 […]

Old blood carries risks for brain

Harmful factors circulating in old blood may be partly responsible for the mental decline that can come with age, a small study in mice suggests. Irina Conboy of the University of California, Berkeley and colleagues devised a new way to mingle blood in two mice that didn’t involve stitching their bodies together, as in previous […]